胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体
规格：1mg/1ml
英文名： EAAT3
别名： Excitatory amino acid transporters 3; Slc1a1; Eaac1; Eaat3; SLC1A1; EAAC1; EAAT3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; EAAC 2; Excit
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EAAT3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞膜
胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体产品介绍：background: This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. Function: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively 胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体regulated by ARL6IP5 (By similarity). Subunit: Interacts with ARL6IP5/PRAF3. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral 胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体cortical layers). Post-translational modifications: Glycosylated. Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A1 subfamily. Gene ID: 6505 Database links: Entrez Gene: 6505 Human Entrez Gene: 20510 Mouse Entrez Gene: 25550 Rat Omim: 133550 Human SwissProt: P43005 Human SwissProt: P51906 Mouse SwissProt: P51907 Rat Unigene: 444915 Human Unigene: 246670 Mouse Unigene: 6384 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胶质细胞谷氨酸胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体运载蛋白3又称：神经/上皮细胞谷氨酸运载蛋白
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid