O-唾液酸糖蛋白内肽酶抗体
规格：1mg/1ml
英文名： OSGEP
别名： FLJ20411; GCPL-1; GCPL1; hOSGEP; KAE1; O sialoglycoprotein endopeptidase; OSGEP; OSGEP_HUMAN; OSGEP1; Pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1; P
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OSGEP
交叉反应：Human, Mouse, Rat, Cow, Zebrafish,
细胞定位：
O-唾液酸糖蛋白内肽酶抗体产品介绍：background: O-sialoglycoprotein endopeptidases cleave the polypeptide backbone of membrane glycoproteins that contain clusters of O-linked sialoglycans. Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein O-唾液酸糖蛋白内肽酶抗体that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine. Function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Tissue Specificity: Widely expressed at low lO-唾液酸糖蛋白内肽酶抗体evel. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas. Similarity: Belongs to the KAE1 / YgjD family. Database links: Entrez Gene: 55644 Human Entrez Gene: 66246 Mouse Entrez Gene: 290028 Rat Omim: 610107 Human SwissProt: Q9NPF4 Human SwissProt: Q8BWU5 Mouse SwissProt: Q9WVS2 Rat Unigene: 525196 Human Unigene: 274791 Mouse Unigene: 27608 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
O-唾液酸糖蛋白内肽酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid