氧固醇结合蛋白1抗体
规格：1mg/1ml
英文名： OSBP1
别名： OSBP 1; OSBP; OSBP1_HUMAN; Oxysterol binding protein 1; Oxysterol-binding protein 1.
分子量： 89kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OSBP1
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
氧固醇结合蛋白1抗体产品介绍：background: Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008] Function: Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates 氧固醇结合蛋白1抗体paratus membrane. When bound to oxysterols, translocates to the periphery of Golgi membranes. Tissue Specificity: Widely expressed. Similarity: Belongs to the OSBP family. Contains 1 PH domain. Gene ID: 5007 Database links: Entrez Gene: 5007 Human Entrez Gene: 76303 Mouse Entrez Gene: 365410 Rat Omim: 167040 Human SwissProt: P22059 Human SwissProt: Q3B7Z2 Mouse Unigene: 597091 氧固醇结合蛋白1抗体Human Unigene: 291279 Mouse Unigene: 107910 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
氧固醇结合蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid