氧固醇结合蛋白样1A抗体
规格：1mg/1ml
英文名： ORP1
别名： FLJ10217; ORP 1; ORP-1; ORP1; OSBL1_HUMAN; OSBP 8; OSBP L1; OSBP related protein 1; OSBP-related protein 1; OSBP8; OSBPL 1; OSBPL 1A; OSBPL 1B; OSBPL1; OSBPL1A; OSBPL1B; Oxysterol binding protein like
分子量： 108kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ORP1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：
氧固醇结合蛋白样1A抗体产品介绍：background: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008] Function: Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Subunit: Interacts with VAPA (By similarity). Interacts氧固醇结合蛋白样1A抗体 with the GTP-bound form of RAB7A. Interacts with OAS1B (By similarity). Subcellular Location: Late endosome. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes. Similarity: Belongs to the OSBP family. Contains 3 ANK repeats. Contains 1 PH domain. Gene ID: 114876 Database links: Entrez Gene: 114876 Human Entrez Gene: 616555 Cow Entrez Gene: 480761 Dog Entrez Gene: 64291 Mouse Entrez 氧固醇结合蛋白样1A抗体Gene: 259221 Rat Omim: 606730 Human SwissProt: Q9BXW6 Human SwissProt: Q91XL9 Mouse SwissProt: Q8K4M9 Rat Unigene: 370725 Human Unigene: 259470 Mouse Unigene: 443224 Mouse Unigene: 178664 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
氧固醇结合蛋白样1A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid