SKIP蛋白抗体
规格：1mg/1ml
英文名： SKIP
别名： 43 kDa form skeletal muscle and kidney enriched inositol phosphatase; Inositol polyphosphate 5-phosphatase K; INP5K_HUMAN; INPP5K; muscle and kidney-enriched inositol phosphatase; PPS; skeletal muscle
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SKIP
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：
SKIP蛋白抗体产品介绍：background: This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008] Function: Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negativelySKIP蛋白抗体 regulate assembly of the actin cytoskeleton. Subcellular Location: Endoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles. Tissue Specificity: Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney. Similarity: Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family. Gene ID: 51763 Database links: Entrez Gene: 51763 Human Entrez Gene: 19062SKIP蛋白抗体 Mouse Entrez Gene: 287533 Rat Omim: 607875 Human SwissProt: Q9BT40 Human SwissProt: Q8C5L6 Mouse Unigene: 632238 Human Unigene: 1458 Mouse Unigene: 7440 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SKIP蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid