易位相关蛋白δ/TRAP-δ抗体
规格:1mg/1ml
英文名: TRAPD
别名: signal sequence receptor delta; Signal sequence receptor subunit delta; SSR delta; SSR4; translocon associated protein delta; TRAP delta; TRAPD.
分子量: 19kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TRAPD
交叉反应:Human, Mouse, Rat,
细胞定位:
易位相关蛋白δ/TRAP-δ抗体产品介绍:background: This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011] Function: Signal sequence receptor delta is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner易位相关蛋白δ/TRAP-δ抗体 with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. Signal sequence receptor delta consists of six exons and is approximately 70 kb telomeric to the ALD gene.易位相关蛋白δ/TRAP-δ抗体 Although alternative splicing of exon 5 has not been detected in human Signal sequence receptor delta, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus. Subcellular Location: Endoplasmic reticulum Database links: Entrez Gene: 6748 Human Omim: 300090 Human SwissProt: P51571 Human Unigene: 409223 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
易位相关蛋白δ/TRAP-δ抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid