SIDT2蛋白抗体
规格:1mg/1ml
英文名: SIDT2
别名: SIDT-2; B930096O19; BC023957; CGI 40; DKFZp686L17253; FLJ90656; MGC36407; MGC58967; RGD1308311; SID1 transmembrane family member 2; SID1 transmembrane family, member 2; SIDT2; SIDT2_HUMAN.
分子量: 93kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SIDT2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
细胞定位:细胞膜
SIDT2蛋白抗体产品介绍:background: SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid long protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid long protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional SIDT2蛋白抗体21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1. Subcellular Location: Lysosome membrane. Post-translational modifications: Glycosylated. Similarity: Belongs to the SID1 family. Gene ID: SIDT2蛋白抗体51092 Database links: Entrez Gene: 51092 Human Entrez Gene: 214597 Mouse Entrez Gene: 315617 Rat SwissProt: Q8NBJ9 Human SwissProt: Q8CIF6 Mouse SwissProt: D3ZEH5 Rat Unigene: 712144 Human Unigene: 379345 Mouse Unigene: 162997 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SIDT2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 通道蛋白 跨膜蛋白 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid