丝氨酸甲基化酶mSHMT抗体
规格：1mg/1ml
英文名： SHMT2
别名： GLY A+; GLYA; glycine auxotroph A, human complement for hamster; Glycine hydroxymethyltransferase; GLYM_HUMAN; mitochondrial; Serine hydroxymethyltransferase 2 (mitochondrial); Serine hydroxymethyltra
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SHMT2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Zebrafish, Guinea Pig,
细胞定位：细胞浆
丝氨酸甲基化酶mSHMT抗体产品介绍：background: This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing r丝氨酸甲基化酶mSHMT抗体esults in multiple transcript variants. [provided by RefSeq, Oct 2009] Function: Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA. Subcellular Location: Mitochondrion. Mitochondrion matrix > mitochondrion nucleoid. Mitochondrion inner membrane. Similarity: Belongs丝氨酸甲基化酶mSHMT抗体 to the SHMT family. Database links: Entrez Gene: 6472 Human Entrez Gene: 108037 Mouse Entrez Gene: 299857 Rat Omim: 138450 Human SwissProt: P34897 Human Unigene: 741179 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丝氨酸甲基化酶mSHMT抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid