17β羟基类固醇脱氢酶12/17β-HSD12抗体
规格：1mg/1ml
英文名： HSD17B12
别名： 12,3-ketoacyl-CoA reductase,short chain; 17 beta HSD 12; 17 beta hydroxysteroid dehydrogenase 12; 17-@beta-HSD XII; 17-@beta-hydroxysteroid dehydrogenase XII; 17-beta-HSD 12; 17-beta-hydroxysteroid de
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HSD17B12
交叉反应：Human, Mouse, Rat, Dog, Cow, Recombinant Fragment Cynomolgus Monkey
细胞定位：
17β羟基类固醇脱氢酶12/17β-HSD12抗体产品介绍：background: This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011] Function: Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion17β羟基类固醇脱氢酶12/17β-HSD12抗体 of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Expressed in most tissues tested. Highly expressed in the ovary and mammary. Expressed in platelets. Similarity: Belongs to the short-chain17β羟基类固醇脱氢酶12/17β-HSD12抗体 dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. Database links: Entrez Gene: 51144 Human Entrez Gene: 84013 Rat Omim: 609574 Human SwissProt: Q53GQ0 Human SwissProt: Q6P7R8 Rat Unigene: 132513 Human Unigene: 203283 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
17β羟基类固醇脱氢酶12/17β-HSD12抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 生长因子和** 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid