HSCB蛋白抗体
规格:1mg/1ml
英文名: HSCB
别名: AI325508; AW049829; dJ366L4.2; DnaJ (Hsp40) homolog, subfamily C member 20; DnaJ homolog subfamily C member 20; DNAJC20; Hsc20; HSC20_HUMAN; hscB; HscB iron sulfur cluster co chaperone homolog; Iron s
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HSCB
交叉反应:Human, Mouse, Rat,
细胞定位:
HSCB蛋白抗体产品介绍:background: HscB is a 235 amino acid mitochondrial protein that functions as a co-chaperone in iron-sulfur cluster formation. Highly expressed in heart, liver and muscle, and belonging to the HscB family, HscB exists as a L-shaped crystal structure resembling E. coli HscB. Human HscB contains an N-terminal mitochondrial targeting signal followed by a J-domain and short loop. The C-terminal domain folds into a compact 3-helix bundle and likely mediates specific interactions with IscU. Containing six exons and five intronsHSCB蛋白抗体, the gene encoding HscB maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Function: May act as a co-chaperone in iron-sulfur cluster assembly in mitochondria. Subcellular Location: Mitochondrion. HSCB蛋白抗体Tissue Specificity: Liver, muscle and heart. Similarity: Belongs to the hscB family. Contains 1 J domain. Database links: Entrez Gene: 150274 Human Omim: 608142 Human SwissProt: Q8IWL3 Human Unigene: 632780 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
HSCB蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid