人类**状瘤病毒HPV116 gp2抗体
规格:1mg/1ml
英文名: HPV116 gp2
别名: Protein E7
分子量: 11kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
免疫原:KLH conjugated synthetic peptide derived from human HPV116 g
交叉反应:Human, Human Papillomavirus (HPV)
细胞定位:
人类**状瘤病毒HPV116 gp2抗体产品介绍:background: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to人类**状瘤病毒HPV116 gp2抗体arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to 人类**状瘤病毒HPV116 gp2抗体achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription Database links: Entrez Gene: 8223418 Human Papillomavirus (HPV) SwissProt: P03129 Human Papillomavirus (HPV) Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
人类**状瘤病毒HPV116 gp2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 免疫学 **及病毒
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid