4-羟基苯丙酮酸氧化酶抗体
规格：1mg/1ml
英文名： 4HPPD
别名： HPD; 4 HPPD; 4 hydroxyphenylpyruvate dioxygenase; 4 hydroxyphenylpyruvic acid oxidase; 4HPPD; GLOD3; glyoxalase domain containing 3; HPPDase; PPD.
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human 4HPPD
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位：细胞浆
4-羟基苯丙酮酸氧化酶抗体产品介绍：background: The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] Function: HPD participates in the tyrosine catabolic pathway by catalyzing the conversion of 4-hydroxyphenylpyruvate to homogentisate. The mechanism of action of HPD involves a decarboxylation step and an oxidation step, followed by a rearrangement step to 4-羟基苯丙酮酸氧化酶抗体form homogentisic acid. Alterations in the structure and activity of HPD are causally related to two different metabolic disorders, the recessively inherited tyrosinemia type III and the dominantly inherited hawkinsinuria. Subcellular Location: Cytoplasmic Database links4-羟基苯丙酮酸氧化酶抗体: Entrez Gene: 3242 Human Entrez Gene: 15445 Mouse Entrez Gene: 29531 Rat Omim: 609695 Human SwissProt: P32754 Human SwissProt: P49429 Mouse SwissProt: P32755 Rat Unigene: 2899 Human Unigene: 439709 Mouse Unigene: 3664 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
4-羟基苯丙酮酸氧化酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid