异染色质蛋白1结合蛋白3抗体
规格:1mg/1ml
英文名: HP1BP3
别名: Heterochromatin protein 1, binding protein 3; HP1 BP74; HP1BP 3; MGC28927; MGC43701; MGC72624; OTTHUMP00000002717; OTTHUMP00000002719; OTTHUMP00000002720; Protein HP1 BP74; RP5 930J4.3.
分子量: 61kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HP1BP3
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位:细胞核
异染色质蛋白1结合蛋白3抗体产品介绍:background: HP1BP3 is a 553 amino acid nuclear and chromosomal protein that exists as a component of heterochromatin. As such, HP1BP3 is involved in chromatin function and structure. Existing as four alternatively spliced isoforms, HP1BP3 undergoes post-translational phosphorylation, most likely by either ATM or ATR. HP1BP3 contains three H15 (linker histone H1/H5 globular) domains and is encoded by a gene that maps to human chromosome 1p36.12. Human chromosome 1 spans 260 million base 异染色质蛋白1结合蛋白3抗体pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Function: HP1BP3 is a component of heterochromatin and may be involved in chromatin structure and function.异染色质蛋白1结合蛋白3抗体 Subcellular Location: Nuclear Database links: Entrez Gene: 50809 Human Entrez Gene: 15441 Mouse Entrez Gene: 313647 Rat SwissProt: Q5SSJ5 Human SwissProt: Q3TEA8 Mouse SwissProt: Q6P747 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
异染色质蛋白1结合蛋白3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 结合蛋白 细胞类型标志物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit