同源盒蛋白B7抗体
规格：1mg/1ml
英文名： HOXB7
别名： AI325018; HHO C1; HHO.C1; homeo box B7; homeo box c1 protein; Homeobox 2C; homeobox B7; Homeobox protein HHO.C1; Homeobox protein Hox-2C; Homeobox protein Hox-B7; Hox 2.3; Hox 2.3, mouse, homolog of;
分子量： 24kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HOXB7
交叉反应：Human, Mouse, Rat, Chicken, Horse, Sheep,
细胞定位：细胞核
同源盒蛋白B7抗体产品介绍：background: The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. A segment of the HoxB7 proximal promoter drives renal expression of reporter genes specifically in the ureteric bud and collecting ducts. Expression levels of HoxB7 are lower in lymph node metastasis-positive cancer tissues 同源盒蛋白B7抗体than negative cancer tissues. These results suggest that aberrant expression of HOX genes is related to the development of breast cancer and malignant behavior of cancer cells. Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Subcellular Location: Nucleus. Similarity: Belongs to the Antp homeobox 同源盒蛋白B7抗体family. Contains 1 homeobox DNA-binding domain. Gene ID: 3217 Database links: Entrez Gene: 3217 Human Entrez Gene: 15415 Mouse Entrez Gene: 497985 Rat Omim: 142962 Human SwissProt: Q9TT89 Cow SwissProt: P09629 Human SwissProt: P09024 Mouse SwissProt: P18864 Rat Unigene: 436181 Human Unigene: 390366 Mouse Unigene: 113631 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
同源盒蛋白B7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid