同源盒蛋白HOXB1抗体
规格：1mg/1ml
英文名： HOXB1
别名： HCFP3; Homeo box 2I; Homeo box B1; Homeobox 2I; Homeobox B1; Homeobox protein Hox B1; Homeobox protein Hox-2I; Homeobox protein Hox-B1; Homeobox protein HoxB1; Homeobox2I; HomeoboxB1; HOX 2; Hox 2.9;
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HOXB1
交叉反应：Human, Mouse, Pig, Rabbit,
细胞定位：细胞核
同源盒蛋白HOXB1抗体产品介绍：background: HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene Hoxb-1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of Hoxb-1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). Hoxb-1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the sonic hedgehog and Mash1 signaling pathways. Hoxb2 is a 同源盒蛋白HOXB1抗体homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human ***** lung development. Hoxb2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, Hoxb2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish. Function: Sequence-specific 同源盒蛋白HOXB1抗体transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Subcellular Location: Nucleus. Similarity: Belongs to the Antp homeobox family. Labial subfamily. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 15407 Mouse SwissProt: P17919 Mouse Unigene: 890 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
同源盒蛋白HOXB1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid