异质核核糖核蛋白H2抗体
规格：1mg/1ml
英文名： hnRNP H2
别名： FTP 3; FTP-3; FTP3; Heterogeneous nuclear ribonucleoprotein H2; HNRH2_HUMAN; hnRNP H2; HNRNPH2; HNRPH2.
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human hnRNP H2
交叉反应：Human, Mouse, Rat, Pig,
细胞定位：细胞核
异质核核糖核蛋白H2抗体产品介绍：background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia 异质核核糖核蛋白H2抗体phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011] Function: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG). Subcellular Location: Nucleus > nucleoplasm. Tissue Specificity: 异质核核糖核蛋白H2抗体Expressed ubiquitously. Similarity: Contains 3 RRM (RNA recognition motif) domains. Gene ID: 3188 Database links: Entrez Gene: 3188 Human Entrez Gene: 56258 Mouse Entrez Gene: 308650 Rat Omim: 300610 Human SwissProt: P55795 Human SwissProt: P70333 Mouse SwissProt: Q6AY09 Rat Unigene: 432485 Human Unigene: 315909 Mouse Unigene: 160642 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
异质核核糖核蛋白H2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid