TOX3蛋白抗体
规格：1mg/1ml
英文名： TOX3
别名： BC052044; C230068E13; CAG trinucleotide repeat-containing gene F9 protein; CAGF9; TNRC9; TOX high mobility group box family member 3; TOX3; TOX3_HUMAN; Trinucleotide repeat containing 9; Trinucleotide
分子量： 63kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TOX3
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位：
TOX3蛋白抗体产品介绍：Function: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region. Subunit: Homodimer. Interacts with CREB1; the interaction is not depolarization dependent. Interacts with CREBBP (via C-terminus) (By similarity). Interacts (via HGM box) with CITED1TOX3蛋白抗体(via C-terminus); the interaction increases estrogen-response element (ERE)-dependent transcription and protection against cell death. Interacts with CREB1 (phosphorylated form). Subcellular Location: Nucleus (Probable). Tissue Specificity: Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe. Similarity: Contains 1 HMG box TOX3蛋白抗体DNA-binding domain. Gene ID: 27324 Database links: Entrez Gene: 27324 Human Entrez Gene: 244579 Mouse Entrez Gene: 291908 Rat Omim: 611416 Human SwissProt: O15405 Human SwissProt: Q80W03 Mouse SwissProt: B7SBD2 Rat Unigene: 460789 Human Unigene: 302755 Mouse Unigene: 41060 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
TOX3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid