LULL1蛋白抗体
规格：1mg/1ml
英文名： LULL1/TOR1AIP2
别名： TOR1AIP2; IFRG15; Interferon responsive gene 15; LULL1; Lumenal domain like LAP1; NET9; RP11-12M5.5; TOR1AIP2; Torsin 1A interacting protein 2; Torsin A interacting protein 2.
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LULL1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
LULL1蛋白抗体产品介绍：background: LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in LULL1蛋白抗体the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Function: Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope. Subunit: Interacts with TOR1A and TOR1B (ATP-bound). Subcellular Location: Endoplasmic reticulum membrane; LULL1蛋白抗体Single-pass membrane protein. Nucleus membrane. Gene ID: 163590 Database links: Entrez Gene: 163590 Human Entrez Gene: 304881 Rat Omim: 614513 Human SwissProt: Q8NFQ8 Human SwissProt: Q6P752 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
LULL1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid