干细胞生长因子SCGF抗体
规格：1mg/1ml
英文名： SCGF
别名： SCGF beta; C type lectin domain family 11 member A; C type lectin superfamily member 3; C-type lectin domain family 11 member A; C-type lectin superfamily member 3; CLC11_HUMAN; CLEC11A; CLECSF3; LSLC
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SCGF
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 分泌型蛋白
干细胞生长因子SCGF抗体产品介绍：background: SCGF is a cytokine for primitive hematopoietic progenitor cells and exhibits species-specific activity. It is predominantly expressed in proliferating chondrocytes, bone marrow cells, the periosteum and the perichondrium of skeletal tissues. SCGF contains an N-terminal Arg-Gly-Asp triplet (RGD triplet), leucine zipper domains, a C-terminal C-type lectin domain and numerous potential glycosylation sites. It has burst-promoting activity and granulocyte/macrophage colony-promoting activity in vitro. SCGF is directly correlated to granulocyte recovery following stem cell transplantation and thus can be an indicator of hematopoietic recovery following stem cell transplantation. Function: Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes,干细胞生长因子SCGF抗体 lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation. Subcellular Location: Cytoplasm. Secreted. Tissue Specificity: Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression干细胞生长因子SCGF抗体were detected in spleen, thymus, appendix and fetal liver. Post-translational modifications: O-glycosylated. Probably sulfated on the O-glycans. Similarity: Contains 1 C-type lectin domain. Gene ID: 6320 Database links: Entrez Gene: 6320 Human Omim: 604713 Human SwissProt: Q9Y240 Human Unigene: 512680 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
干细胞生长因子SCGF抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 干细胞 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid