SBNO2蛋白抗体
规格：1mg/1ml
英文名： SBNO2
别名： FLJ00173; KIAA0963; Protein strawberry notch homolog 2; SBNO2; Sno; Stno.
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SBNO2
交叉反应：Human, Mouse, Rat,
细胞定位：
SBNO2蛋白抗体产品介绍：background: SBNO2 is a 1,366 amino acid protein that belongs to the SBNO family. Detected in macrophages, SBNO2 seems to have transcriptional repression activity. SBNO2 and ETV3 are components of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. The expression of SBNO2 is regulated by IL-10 in a STAT3-dependent way. Existing as two alternatively spliced isoforms, the SBNO2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish and C.elegans,SBNO2蛋白抗体 and maps to human chromosome 19p13.3. GPx-4 and LKB1 are neighbors of SBNO2 on chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes haveSBNO2蛋白抗体 been linked to chromosome 19. Function: SBNO2 appears to have transcriptional repression activity in macrophages. Database links: Entrez Gene: 22904 Human SwissProt: Q9Y2G9 Human Unigene: 408708 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SBNO2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid