二胺乙酰基转移酶1抗体
规格：1mg/1ml
英文名： SAT1
别名： DC21; Diamine acetyltransferase 1; EC 2.3.1.57; KFSD; Polyamine N acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; SAT; SAT1; SAT1_HUMAN; Spermidine/spermine N(1) ac
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SAT1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Xenopus laevis
细胞定位：细胞浆
二胺乙酰基转移酶1抗体产品介绍：background: The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009] Function: Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation 二胺乙酰基转移酶1抗体of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine. Subcellular Location: Cytoplasm. DISEASE: Defects in SAT1 may be a cause of keratosis follicularis spinulosa decalvans X-linked (KFSDX) [MIM:308800]. A rare disorder affecting the skin and the eye. Affected men show thickening of the skin of the neck, ears, and extremities, especially the palms and soles, loss of eyebrows, eyelashes and beard, thickening of the eyelids with blepharitis and ectropion, and corneal degeneration. Similarity: Belongs to the acetyltransferase family. Contains 二胺乙酰基转移酶1抗体1 N-acetyltransferase domain. Gene ID: 6303 Database links: Entrez Gene: 6303 Human Entrez Gene: 20229 Mouse Entrez Gene: 302642 Rat Entrez Gene: 567881 Zebrafish Omim: 313020 Human SwissProt: Q8AXL1 Chicken SwissProt: Q3T0Q0 Cow SwissProt: P21673 Human SwissProt: P48026 Mouse SwissProt: Q28999 Pig SwissProt: P45380 Rat Unigene: 9589 Chicken Unigene: 28491 Human Unigene: 2734 Mouse Unigene: 455898 Mouse Unigene: 474481 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
二胺乙酰基转移酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid