线粒体SARS2抗体
规格:1mg/1ml
英文名: SARS2
别名: mitochondrial; mtSerRS; SARS; SARS2; SARSM; Serine tRNA ligase; Serine--tRNA ligase; SerRS; SerRSmt; SERS; Seryl tRNA synthetase 2; Seryl-tRNA synthetase; Seryl-tRNA(Ser/Sec) synthetase; SYS; SYSM_HUM
分子量: 68kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SARS2
交叉反应:Human, Mouse, Rat,
细胞定位:
线粒体SARS2抗体产品介绍:background: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to 线粒体SARS2抗体this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009] Function: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). Subcellular Location: Mitochondrion matrix. Similarity: Belongs 线粒体SARS2抗体to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily. Database links: Entrez Gene: 54938 Human Omim: 612804 Human SwissProt: Q9NP81 Human Unigene: 709416 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体SARS2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid