特异性雄**调节蛋白抗体
规格:1mg/1ml
英文名: SARG
别名: SARG; C1orf116; Chromosome 1 open reading frame 116; DKFZp666H2010; FLJ36507; MGC2742; MGC4309; OTTHUMP00000034747; Specifically androgen regulated gene protein; Specifically androgen regulated protei
分子量: 37kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SARG
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat,
细胞定位:细胞浆
特异性雄**调节蛋白抗体产品介绍:background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome 特异性雄**调节蛋白抗体are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf116 gene product has been provisionally designated C1orf116 pending further characterization. Function: 特异性雄**调节蛋白抗体C1orf116 belongs to the SARG family. It is a putative androgen-specific receptor. It is highly expressed in prostate. Subcellular Location: Cytoplasmic Database links: Entrez Gene: 79098 Human Omim: 611680 Human SwissProt: Q9BW04 Human SwissProt: Q8BI29 Mouse SwissProt: Q499V8 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
特异性雄**调节蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 染色质和核信号 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid