连接粘附分子2抗体
规格：1mg/1ml
英文名： JAM2
别名： Junctional Adhesion Molecule 2; C21orf43; CD 322; CD322; CD322 antigen; JAM 2; JAM B; JAM IT/VE JAM; JAM, vascular endothelial; JAM-2; JAM-B; JAM2; JAM2_HUMAN; JAMB; Jcam2; Junction adhesion molecule
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human JAM2
交叉反应：Mouse, Rat, Cow, Rabbit, Chimpanzee, Macaque Monkey, Gorilla, Orangutan
细胞定位：细胞膜
连接粘附分子2抗体产品介绍：background: This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012] Function: May play a role in the processes of lymphocyte homing to secondary lymphoid organs. Subcellular Location: Cell junction > tight junction. 连接粘附分子2抗体Cell membrane. Localized at tight junctions of both epithelial and endothelial cells. Tissue Specificity: Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells. Similarity: Belongs to the immunoglobulin superfamily. Contains 1 Ig-like C2-type 连接粘附分子2抗体(immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Database links: Entrez Gene: 538846 Cow Entrez Gene: 58494 Human Entrez Gene: 67374 Mouse Entrez Gene: 619374 Rat Omim: 606870 Human SwissProt: P57087 Human SwissProt: Q9JI59 Mouse Unigene: 517227 Human Unigene: 41758 Mouse Unigene: 6473 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
连接粘附分子2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 发育生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid