前列腺雄**调节蛋白抗体
规格:1mg/1ml
英文名: JTB
别名: hJT; HJTB; HSPC222; JTB; JTB_HUMAN; Jumping translocation breakpoint; Jumping translocation breakpoint protein; OTTHUMP00000034759; PAR; PAR protein; Prostate androgen regulated protein; Prostate andr
分子量: 13kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human JTB
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆 细胞膜
前列腺雄**调节蛋白抗体产品介绍:background: Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential. Subcellular Location: Membrane. Mitochondrion. Cytoplasm.前列腺雄**调节蛋白抗体 Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase. Tissue Specificity: Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts. Similarity: Belongs to the JTB前列腺雄**调节蛋白抗体 family. Gene ID: 10899 Database links: Entrez Gene: 10899 Human Entrez Gene: 23922 Mouse Entrez Gene: 29439 Rat Omim: 604671 Human SwissProt: O76095 Human SwissProt: O88824 Mouse SwissProt: O88823 Rat Unigene: 6396 Human Unigene: 13912 Mouse Unigene: 91803 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
前列腺雄**调节蛋白抗体研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid