JRK蛋白抗体
规格：1mg/1ml
英文名： JRK
别名： Jerky; Jerky (mouse) homolog; Jerky homolog (mouse); JH8.
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human JRK
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
JRK蛋白抗体产品介绍：background: This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Function: The JRK gene is the human homolog of the mouse jerky gene. The encoded protein has similarity to several nuclear regulatory proteins, including centromere protein B, which indicates that it might function as a DNA binding protein. Insertional inactivation JRK蛋白抗体of this gene in transgenic mice results in epileptic seizures. JRK is a strong candidate for Childhood Absence Epilepsy (CAE) as it has been mapped to the same chromosomal location (8q24.3). Two transcript variants encoding different isoforms have been found for this gene. Subcellular Location: Nuclear Database links: Entrez Gene: 8629 Human Omim: 603210 Human SwissProt: O75564 Human Unigene: 535903 Human UnigeneJRK蛋白抗体: 683465 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
JRK蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid