JOSD1蛋白抗体
规格:1mg/1ml
英文名: Josephin-1
别名: dJ508I15.2; JOS1_HUMAN; Josd1; Josephin 1; Josephin domain containing 1; Josephin domain-containing 1; Josephin-1; KIAA0063; OTTHUMP00000198984; OTTHUMP00000239365.
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human JOSD1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Cat,
细胞定位:
JOSD1蛋白抗体产品介绍:background: Josephin-1 is a 202 amino acid protein that contains one josephin domain and is encoded by a gene that maps to human chromosome 22. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of theJOSD1蛋白抗体 Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. Function: Has low protease activity towards poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme. Subunit: Interacts with beta-actin/ACTB. Similarity: Contains 1 Josephin domain. Gene ID: 9929 Database links: Entrez Gene:JOSD1蛋白抗体 9929 Human Entrez Gene: 74158 Mouse Entrez Gene: 315134 Rat SwissProt: Q15040 Human SwissProt: Q9DBJ6 Mouse SwissProt: Q5BJY4 Rat Unigene: 3094 Human Unigene: 2495 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
JOSD1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 泛素
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid