IZUMO1蛋白抗体
规格：1mg/1ml
英文名： IZUMO1
别名： IZUM1_HUMAN; IZUMO; Izumo sperm egg fusion 1; Izumo sperm-egg fusion protein 1; Izumo1; MGC34799; OBF; Oocyte binding/fusion factor; Sperm specific protein izumo; Sperm-specific protein izumo.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IZUMO1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
IZUMO1蛋白抗体产品介绍：background: The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008] Function: Involved in the fertilization process. May be involved in the fusion of the sperm with the egg. Subunit: Monomer, homodimer and homooligomer. Interacts with IZUMO1R/JUNO (By similarity). Subcellular Location: Membrane. Tissue Specificity: Sperm-specific (at protein level).IZUMO1蛋白抗体 Detectable on sperm surface only after the acrosome reaction. Post-translational modifications: N-glycosylated. Glycosylation is not essential for fusion and for proper protein trafficking in sperm. Phosphorylated. Similarity: Belongs to the Izumo family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Gene ID: 284359 Database links: Entrez Gene: 284359 Human Entrez Gene: 73456 Mouse Entrez Gene: 499152 Rat Omim:IZUMO1蛋白抗体 609278 Human SwissProt: Q8IYV9 Human SwissProt: Q9D9J7 Mouse SwissProt: Q6AY06 Rat Unigene: 400688 Human Unigene: 380445 Mouse Unigene: 125416 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
IZUMO1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid