p53相关蛋白激酶结合蛋白抗体
规格：1mg/1ml
英文名： TPRKB
别名： CGI 121; My019; PRPK (p53 related protein kinase) binding protein; PRPK-binding protein; TP53RK binding protein; TP53RK-binding protein; Tprkb; TPRKB_HUMAN.
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TPRKB
交叉反应：Human, Mouse, Rat, Dog, Rabbit,
细胞定位：细胞核 细胞浆
p53相关蛋白激酶结合蛋白抗体产品介绍：Function: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification (By similarity). Subunit: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes. Interacts with TP53RK/PRPK.p53相关蛋白激酶结合蛋白抗体 Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Widely expressed. Similarity: Belongs to the CGI121/TPRKB family. Gene ID: 51002 Database links: Entrez Gene: 425906 Chicken Entrez Gene: 519224 Cow Entrez Gene: 475794 Dog Entrez Gene: p53相关蛋白激酶结合蛋白抗体51002 Human Entrez Gene: 69786 Mouse Entrez Gene: 297411 Rat Omim: 608680 Human SwissProt: Q9Y3C4 Human SwissProt: Q8QZZ7 Mouse SwissProt: Q5PQR8 Rat Unigene: 157401 Human Unigene: 218434 Mouse Unigene: 203015 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
p53相关蛋白激酶结合蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid