肿瘤蛋白p53诱导核内蛋白2抗体
规格:1mg/1ml
英文名: TP53INP2
别名: C20orf110; Diabetes and obesity regulated; p53 inducible protein U; DOR; p53-inducible protein U; PIG-U; PINH; T53I2_HUMAN; Tp53inp2; Tumor protein p53-inducible nuclear protein 2.
分子量: 24kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TP53INP2
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
肿瘤蛋白p53诱导核内蛋白2抗体产品介绍:Function: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase 肿瘤蛋白p53诱导核内蛋白2抗体class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. Subunit: Interacts with VMP1, GABARAP, GABARAPL1, GABARAPL2, MAP1LC3A, MAP1LC3B, MAP1LC3C and THRA. Subcellular Location: Nucleus. Gene ID: 58476 Database links: Entrez Gene: 58476 Human Entrez Gene: 68728 Mouse Entrez Gene: 362246 Rat SwissProt: Q8IXH6 Human SwissProt:肿瘤蛋白p53诱导核内蛋白2抗体 Q8CFU8 Mouse SwissProt: Q8CHM3 Rat Unigene: 516994 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤蛋白p53诱导核内蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 染色质和核信号 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid