突触17抗体
规格：1mg/1ml
英文名： STX17
别名： FLJ20651; MGC102796; MGC126613; MGC126615; Stx17; STX17_HUMAN; Syntaxin 17; Syntaxin-17.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human STX17
交叉反应：Human, Mouse, Rat, Pig, Rabbit, Sheep,
细胞定位：细胞膜
突触17抗体产品介绍：background: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 17, also known as STX17, is a 302 amino acid single-pass type IV membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the syntaxin family. Thought to localize to the endoplasmic reticulum, Syntaxin 17 plays a role in vesicle trafficking to lysosomes and may be involved in processes related to cell division. The gene encoding Syntaxin 17 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family突触17抗体 gene cluster. Function: Implicated in vesicle trafficking to lysosomes. Could be involved in processes related to cell division. Subcellular Location: Membrane. Appears to be associated with a membrane compartment, perhaps a subset of the ER such as exit or entrance sites. Similarity: Belongs to the syntaxin family. Contains 1 t-SNARE coiled-coil homology domain. Gene ID: 55014 Database links: Entrez Gene: 55014 Human 突触17抗体Omim: 604204 Human SwissProt: P56962 Human Unigene: 704031 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触17抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid