LARP1蛋白抗体
规格:1mg/1ml
英文名: LARP1
别名: 1810024J12Rik; 3110040D16Rik; KIAA0731; La related protein; La ribonucleoprotein domain family, member 1; LARP; MGC19556; mKIAA0731; rCG_32791; RGD1306683; RP23-293I3.7.
分子量: 124kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LARP1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
细胞定位:
LARP1蛋白抗体产品介绍:background: LARP1 is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3. WidelyLARP1蛋白抗体 expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing. Function: LARP1 belongs to the LARP family and contains 1 HTH La-type RNA-binding domain. Subunit: Interacts with PABPC1/PABP. Associates with the mTORC1LARP1蛋白抗体 complex. Interacts with EIF4E. Subcellular Location: Cytoplasm Similarity: Belongs to the LARP family. Contains 1 HTH La-type RNA-binding domain. Gene ID: 23367 Database links: Entrez Gene: 23367 Human Omim: 612059 Human SwissProt: Q6PKG0 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
LARP1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 细胞凋亡 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid