KAZALD1蛋白抗体
规格：1mg/1ml
英文名： KAZALD1
别名： Kazal-type serine protease inhibitor domain-containing protein 1; KAZALD1; KAZD1_HUMAN.
分子量： 30kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KAZALD1
交叉反应：Human, Mouse, Rat, Chicken,
细胞定位：分泌型蛋白
KAZALD1蛋白抗体产品介绍：background: BONO1, also known as KAZALD1 (kazal-type serine protease inhibitor domain-containing protein 1), IGFBP-rP10, FKSG28 or FKSG40, is a 304 amino acid secreted extracellular matrix protein that promotes matrix assembly. BONO1 is expressed in developing bones and odontoblasts in teeth, where it plays a role in osteoblast proliferation during bone formation and regeneration. BONO1 is also expressed at high levels in spleen, and is found at lower levels in lung, skin, urinary bladder, brain, tongue, kidney and large intestine. Existing as two alternatively spliced isoforms, BONO1 contains one Kazal-like domain, an IGFBP N-terminal domain and a single Ig-like KAZALD1蛋白抗体C2-type (immunoglobulin-like) domain. The gene encoding BONO1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides. Cockayne syndrome, Cockayne syndrome and trisomy 10 are associated with defects in chromosome 10. Function: Involved in the proliferation of osteoblasts during bone formation and bone regeneration. Promotes matrix assembly. Subcellular Location: Secreted > KAZALD1蛋白抗体extracellular space > extracellular matrix. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 Kazal-like domain. Gene ID: 81621 Database links: Entrez Gene: 81621 Human SwissProt: Q96I82 Human Unigene: 534859 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KAZALD1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid