钾离子通道Kir2.2抗体
规格:1mg/1ml
英文名: Kir2.2
别名: ATP sensitive inward rectifier potassium channel 12; ATP-sensitive inward rectifier potassium channel 12; hIRK; Human high conductance inward rectifier potassium channel alpha; Inward rectifier K; Inw
分子量: 49kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Kir2.2
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
钾离子通道Kir2.2抗体产品介绍:background: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current b钾离子通道Kir2.2抗体y internal magnesium. Can be blocked by extracellular barium and cesium. Subcellular Location: Membrane. Similarity: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily. Gene ID: 3768 Database links: Entrez Gene: 403760 Dog Entrez钾离子通道Kir2.2抗体 Gene: 100131509 Human Entrez Gene: 100290070 Human Entrez Gene: 3768 Human Entrez Gene: 16515 Mouse Entrez Gene: 117052 Rat Omim: 602323 Human SwissProt: Q4TZY1 Cow SwissProt: Q14500 Human SwissProt: P52187 Mouse SwissProt: P52188 Rat Unigene: 200629 Human Unigene: 4970 Mouse Unigene: 10406 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钾离子通道Kir2.2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 细胞膜受体
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid