驱动蛋白C3抗体
规格：1mg/1ml
英文名： KIFC3
别名： DKFZp686D23201; FLJ34694; Kifc3; KIFC3_HUMAN; Kinesin family member C3; Kinesin-like protein KIFC3.
分子量： 83kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIFC3
交叉反应：Human,
细胞定位：细胞浆
驱动蛋白C3抗体产品介绍：background: KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 [PubMed 9782090]).[supplied by OMIM, Mar 2009] Function: Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity).驱动蛋白C3抗体 Required for zonula adherens maintenance. Subcellular Location: Cell junction > adherens junction. Cytoplasm > cytoskeleton > centrosome. Cytoplasmic vesicle membrane. Apical cell membrane. On membrane organelles immediately beneath the apical plasma membrane of renal tubular epithelial cells. Localized in the distal tubules and loops of Henle in the kidney, but not in the proximal tubules or the glomeruli, with stronger staining in the apical area of these epithelial cells (By similarity). Localizes along zonula adherens only at mature cell-cell contacts. Similarity: Belongs to the驱动蛋白C3抗体 kinesin-like protein family. Contains 1 kinesin-motor domain. Gene ID: 3801 Database links: Entrez Gene: 3801 Human Entrez Gene: 16582 Mouse Entrez Gene: 307644 Rat Omim: 604535 Human SwissProt: Q9BVG8 Human SwissProt: O35231 Mouse Unigene: 23131 Human Unigene: 378951 Mouse Unigene: 14753 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
驱动蛋白C3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid