磷酸化驱动蛋白家族成员22抗体
规格：1mg/1ml
英文名： phospho-KIF22 (Ser427)
别名： KIF22 (phospho S427); p-KIF22 (phospho S427); p-KID (Ser 427); A 328A3.2; KID; KIF 22; kif22; KIF22_HUMAN; Kinesin family member 22; Kinesin like 4; Kinesin like DNA binding protein; Kinesin like DNA
分子量： 73kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated Synthesised phosphopeptide derived from human
交叉反应：Human,
细胞定位：细胞核 细胞浆
磷酸化驱动蛋白家族成员22抗体产品介绍：background: The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Function: Kinesin family that is involved in spindle formation and the movements of chromosomes 磷酸化驱动蛋白家族成员22抗体during mitosis and meiosis. Binds to microtubules and to DNA. Subcellular Location: Nucleus. Cytoplasm > cytoskeleton. Post-translational modifications: Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. 磷酸化驱动蛋白家族成员22抗体Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. Database links: Entrez Gene: 3835 Human Omim: 603213 Human SwissProt: Q14807 Human Unigene: 612151 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化驱动蛋白家族成员22抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid