KIAA1618蛋白抗体
规格：1mg/1ml
英文名： KIAA1618
别名： ALK lymphoma oligomerization partner on chromosome 17; ALO17; RN213_HUMAN; Hypothetical protein LOC57714; Protein ALO17.
分子量： 591kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIAA1618
交叉反应：Human,
细胞定位：
KIAA1618蛋白抗体产品介绍：background: There are three isoforms. A chromosomal aberration involving KIAA1618 is associated with anaplastic large-cell lymphoma (ALCL). Translocation t(2;17)(p23;q25) with ALK. Function: Probable E3 ubiquitin-protein ligase that may play a role in angiogenesis. May also have an ATPase activity. Subcellular Location: Cytoplasm Tissue Specificity: Widely expressed (at protein level). Post-translational modifications: Autoubiquitinates. DISEASE: Moyamoya disease 2 (MYMY2) [MIM:607151]: A progressive cerebral angiopathy characterized by bilateral intracranial carotid artery stenosis and telangiectatic vessels in the region of the basal ganglia. The abnormal KIAA1618蛋白抗体vessels resemble a 'puff of smoke' (moyamoya) on cerebral angiogram. Affected individuals can develop transient ischemic attacks and/or cerebral infarction, and rupture of the collateral vessels can cause intracranial hemorrhage. Hemiplegia of sudden onset and epileptic seizures constitute the prevailing presentation in childhood, while subarachnoid bleeding occurs more frequently in *****s. {ECO:0000269|PubMed:21048783, KIAA1618蛋白抗体ECO:0000269|PubMed:21799892}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Similarity: Contains 1 RING-type zinc finger. Gene ID: 57714 Database links: Entrez Gene: 57714 Human SwissProt: Q9HCF4 Human Unigene: 514554 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KIAA1618蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid