KIAA1543蛋白抗体
规格：1mg/1ml
英文名： KIAA1543
别名： Calmodulin regulated spectrin associated protein family, member 3; Calmodulin-regulated spectrin-associated protein 3; CAMP3_HUMAN; KIAA1543; NEZHA; Protein Nezha.
分子量： 134kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIAA1543
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
KIAA1543蛋白抗体产品介绍：background: Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and KIAA1543蛋白抗体insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. The KIAA1543 gene product has been provisionally designated KIAA1543 pending further characterization. Function: Microtubule minus-end binding protein that acts as a regulator of microtubule dynamics. Specifically required for zonula adherens biogenesis and maintenance by anchoring microtubules at their minus-ends to zonula adherens, leading toKIAA1543蛋白抗体 recruit KIFC3 kinesin to junctional site. Subcellular Location: Cell junction > adherens junction. Cytoplasm. Cytoplasm > cytoskeleton. Scattered in the cytoplasm. Localizes along zonula adherens only at mature cell-cell contacts. Similarity: Belongs to the CAMSAP1 family. Contains 1 CH (calponin-homology) domain. Contains 1 CKK domain. Gene ID: 57662 Database links: Entrez Gene: 57662 Human Omim: 612685 Human SwissProt: Q9P1Y5 Human Unigene: 17686 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KIAA1543蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid