KIAA1161蛋白抗体
规格：1mg/1ml
英文名： KIAA1161
别名： K1161_HUMAN; KIAA1161; Uncharacterized family 31 glucosidase KIAA1161.
分子量： 81kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIAA1161
交叉反应：Human, Mouse, Rat, Dog, Horse, Rabbit,
细胞定位：细胞膜
KIAA1161蛋白抗体产品介绍：background: KIAA1161 is a 714 amino acid protein that belongs to the glycosyl hydrolase 31 family and functions as a putative glucosidase. This single-pass type II membrane protein is post-translationally phosphorylated at serine 44 and glycosylated at amino acid positions 240 and 250. The gene encoding KIAA1161 maps to human chromosome 9, which consists of about 145 million bases, comprises approximately 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. KIAA1161蛋白抗体Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation lKIAA1161蛋白抗体eading to the aberrant production of BCR-ABL fusion protein often found in leukemias. Function: Putative glucosidase. Subcellular Location: Membrane. Similarity: Belongs to the glycosyl hydrolase 31 family. Gene ID: 57462 Database links: Entrez Gene: 57462 Human Entrez Gene: 329828 Mouse SwissProt: Q6NSJ0 Human SwissProt: Q69ZQ1 Mouse Unigene: 522083 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产KIAA1161蛋白抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 新陈代谢 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid