KIAA0146蛋白抗体
规格:1mg/1ml
英文名: KIAA0146
别名: K0146_HUMAN; KIAA0146; Uncharacterized protein KIAA0146.
分子量: 100kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KIAA0146
交叉反应:Human, Mouse, Cow, Horse,
细胞定位:
KIAA0146蛋白抗体产品介绍:Function: Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity. Subunit: Found in a complex,KIAA0146蛋白抗体 at least composed of BLM, RAD51 and SPIDR; the complex formation is mediated by SPIDR.Interacts (via C-terminal region) with BLM; the interaction is direct. Interacts with RAD51; the interaction is direct. Interacts (via the C-terminal region) with FIGNL1 (via N-terminal one-half region); the interaction is direct. Subcellular Location: Nucleus Gene ID: 23514 Database links: Entrez Gene: 23514 Human SwissProt: Q14159KIAA0146蛋白抗体 Human Unigene: 381058 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KIAA0146蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid