肾细胞癌抗原NYREN 45抗体
规格:1mg/1ml
英文名: KCTD3
别名: BTB/POZ domain-containing protein KCTD3; Kctd3; KCTD3_HUMAN; MGC43935; NY REN 45; NY REN 45 antigen; NY REN45; NYREN 45; OTTHUMP00000035070; Potassium channel tetramerisation domain containing 3; Rena
分子量: 89kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KCTD3
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位:
肾细胞癌抗原NYREN 45抗体产品介绍:background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher 肾细胞癌抗原NYREN 45抗体syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. Tissue Specificity: Broadly expressed in normal tissues. Similarity: Belongs to the KCTD3 family. Contains 1 BTB (POZ) domain.肾细胞癌抗原NYREN 45抗体 Contains 5 WD repeats. Gene ID: 51133 Database links: Entrez Gene: 51133 Human Entrez Gene: 226823 Mouse Entrez Gene: 305055 Rat Omim: 613272 Human SwissProt: Q9Y597 Human SwissProt: Q8BFX3 Mouse Unigene: 335139 Human Unigene: 209880 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肾细胞癌抗原NYREN 45抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 神经生物学 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid