KCNH5蛋白抗体
规格:1mg/1ml
英文名: KCNH5
别名: EAG2; Ether a go go potassium channel 2; H EAG2; HGNC:6254; Kv10.2; potassium voltage gated channel subfamily H (eag-related) member 5; Voltage gated potassium channel subunit Kv10.2.
分子量: 112kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KCNH5
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞膜
KCNH5蛋白抗体产品介绍:background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNH5 gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH5 is not expressed in differentiating myoblasts. Subunit: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH5蛋白抗体KCNH1/EAG (Probable). Subcellular Location: Cell Membrane: multi-pass membrane protein. Tissue Specificity: Detected in brain, skeletal muscle, heart,placenta, lung and liver, and at low levels in kidney. Similarity: Belongs to the potassium channel family. Contains 1 cyclic nucleotide-binding domain. Contains 1 PAS (PER-ARNT-SIM) domain. Contains 1 cyclic nucleotide-binding domain. ] Contains 1 PAS (PER-ARNT-SIM) KCNH5蛋白抗体domain. Gene ID: 27133 Database links: Entrez Gene: 27133 Human Entrez Gene: 238271 Mouse Entrez Gene: 171146 Rat Omim: 605716 Human SwissProt: Q8NCM2 Human SwissProt: Q6NZH0 Mouse SwissProt: Q920E3 Mouse SwissProt: Q9EPI9 Rat Unigene: 27043 Human Unigene: 48753 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KCNH5蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 通道蛋白 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid