KCNH4蛋白抗体
规格：1mg/1ml
英文名： KCNH4
别名： BEC2; Brain-specific eag-like channel 2; ELK channel 1; ELK channel 1; brain-specific eag-like channel 2; ELK1; Ether-a-go-go K(+) channel family member; Ether-a-go-go-like potassium channel 1; Kv12.3
分子量： 112kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNH4
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
KCNH4蛋白抗体产品介绍：background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system. [provided by RefSeq, Jul 2008] Function: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current, but shows no inactivation. ChannelKCNH4蛋白抗体 properties may be modulated by cAMP and subunit assembly. Subunit: he potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Detected only in brain, in particular in the telencephalon. Detected in putamen and caudate nucleus, and at lower KCNH4蛋白抗体levels in cerebral cortex, occipital and hippocampus. Similarity: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv12.3/KCNH4 sub-subfamily. Contains 1 cyclic nucleotide-binding domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain. Gene ID: 23415 Database links: Entrez Gene: 23415 human Entrez Gene: 114032 Rat SwissProt: Q9R1T9 Rat Swiss-Prot: Q9UQ05.1 human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KCNH4蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid