KCNH3蛋白抗体
规格：1mg/1ml
英文名： KCNH3
别名： BEC1; Brain-specific eag-like channel 1; ELK channel 2; ELK2; Ether-a-go-go-like potassium channel 2; Kv12.2; Melk2; Potassium voltage-gated channel, subfamily H (eag-related), member 3; Voltage-gated
分子量： 117kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNH3
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞膜
KCNH3蛋白抗体产品介绍：background: Voltage gated potassium (Kv) channels represent the most complex class of voltage gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH3 is a pore forming (alpha) subunit of voltage-gated potassium channel. It elicits an outward current with fast inactivation. Subunit: The potassium KCNH3蛋白抗体channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Subcellular Location: Membrane; Multipass membrane protein. Tissue Specificity: Detected only in brain, in particular in the telencephalon. Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus. Similarity: Contains 1 cyclic nucleotide-binding domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain. Gene ID: 23416KCNH3蛋白抗体 Database links: Entrez Gene: 23416 Human Entrez Gene: 16512 Mouse Entrez Gene: 27150 Rat Omim: 604527 Human SwissProt: Q9ULD8 Human SwissProt: Q9WVJ0 Mouse SwissProt: O89047 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KCNH3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid