精氨酸脱羧酶抗体
规格：1mg/1ml
英文名： ODCp
别名： L-Arginine decarboxylase; ADC; ADC_HUMAN; Antizyme inhibitor 2; ArgDC; Arginine decarboxylase; AZI2; KIAA1945; L-Arginine carboxy lyase; ODC antizyme inhibitor 2; ODC paralog; ODC-p; ODC-paralogue; OD
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ODCp
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
精氨酸脱羧酶抗体产品介绍：background: ODCp is a 460 amino acid protein that is expressed in brain and testis. ODCp is a member of the Orn/Lys/Arg decarboxylase class-II family that catalyzes the creation of CO2 and agmatine from L-arginine. Mammalian ODCp differs from the forms expressed in bacteria and plants and shares less than 50% homology with Ornithine decarboxylase (ODC). ODCp is associated with the mitochondrial membrane where excess agmatine can be degraded by the enzyme Agmatinase or bound by the imidazoline recepto. In the brain, the highest levels of ODCp are found in the hypothalamus. Mammalian ODCp is thermally unstable and can be inhibited by Ca2+, Co2+ and polyamines. Function: Decarboxylates L-arginine to agmatine. Truncated splice isoforms probably lack activity. Subunit: Interacts with OAZ1, OAZ2 and 精氨酸脱羧酶抗体OAZ3; the interactions stabilize the complex by inhibiting AZIN2 ubiquitination and degradation. Does not form an heterodimer with ODC1 (By similarity). Monomer. Interaction with OAZ1, OAZ2 and OAZ3; the interactions lead to increased ornithine decarboxylase (ODC)activity and decreased rate of ODC1 degradation. Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in brain. Also expressed in testis. Similarity精氨酸脱羧酶抗体: Belongs to the Orn/Lys/Arg decarboxylase class-II family. Gene ID: 113451 Database links: Entrez Gene: 506961 Cow Entrez Gene: 478144 Dog Entrez Gene: 113451 Human Entrez Gene: 242669 Mouse Entrez Gene: 366473 Rat Omim: 608353 Human SwissProt: Q96A70 Human SwissProt: Q8BVM4 Mouse Unigene: 101807 Human Unigene: 215814 Mouse Unigene: 50921 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
精氨酸脱羧酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid