电压门控钾通道Kv1.2抗体
规格:1mg/1ml
英文名: Kv1.2
别名: Akr6a4; BK2; HBK5; HK4; HUKIV; Kca1 2; kcna2; KV1.2; MGC50217; Mk 2; MK2; NGK1; Potassium voltage gated channel shaker related subfamily member 2; Potassium voltage-gated channel subfamily A member 2;
分子量: 57kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Kv1.2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞膜
电压门控钾通道Kv1.2抗体产品介绍:background: Kv1.2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments. Function: Mediates the voltage-dependent电压门控钾通道Kv1.2抗体 potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Subunit: Heterotetramer of potassium channel proteins. Subcellular Location: Membrane; Multi-pass membrane 电压门控钾通道Kv1.2抗体protein Similarity: Belongs to the potassium channel family. Gene ID: 3737 Database links: Entrez Gene: 395117 Chicken Entrez Gene: 3737 Human Entrez Gene: 16490 Mouse Entrez Gene: 25468 Rat Omim: 176262 Human SwissProt: P16389 Human SwissProt: P63141 Mouse SwissProt: P63142 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
电压门控钾通道Kv1.2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 神经生物学 通道蛋白 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid