骨髓增生异常综合征相关蛋白抗体
规格：1mg/1ml
英文名： KTEL1
别名： C3orf9; CAP10 like 46 kDa protein; CAP10 like protein, 46 kDa; CLP46; hCLP46; KDELC family like 1; KDELCL1; KTEL (Lys Tyr Glu Leu) containing 1; KTEL motif containing protein 1; KTELC1; MDS010; MDSRP;
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KTEL1
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：
骨髓增生异常综合征相关蛋白抗体产品介绍：background: CLP46 is a KTEL motif-containing protein that belongs to the CAP10 family. The KTEL motif at the C-terminus of CLP46 is an endoplasmic reticulum (ER) retention signal which localizes the CLP46 protein to the lumen of the ER. CLP46 is thought to promote cell proliferation and is also believed to be involved with hepatic functions. The Drosophila protein rumi, a CAP10 protein and likely similar in function to CLP46, uses glucosylation to act as a Notch signaling regulator. Expressed in varying degrees in most ***** tissue, CLP46 is especially abundant in the liver. CLP46 is not expressed in detectable levels in colon, thymus or small intestine. Human CLP46 shares 94% and 91% sequence similarity with its bovine and mouse homologs, respectively. Function: UDP-glucosyltransferase. Subcellular Location:骨髓增生异常综合征相关蛋白抗体 Endoplasmic reticulum lumen. Tissue Specificity: Expressed in most ***** tissues at different intensities. Abundantly expressed in liver. Expressed also in brain, heart, skeletal muscle, spleen, kidney, placenta, lung and peripheral blood leukocyte. Not detectable in colon, thymus and small intestine. Similarity: Belongs to the glycosyltransferase 90 family. Gene ID: 56983 Database links: Entrez Gene骨髓增生异常综合征相关蛋白抗体: 56983 Human Entrez Gene: 224143 Mouse Entrez Gene: 288091 Rat SwissProt: Q8NBL1 Human SwissProt: Q8BYB9 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骨髓增生异常综合征相关蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid