钙粘蛋白相关的神经受体1抗体
规格：1mg/1ml
英文名： CNR1
别名： Cannabinoid Receptor I; CANN 6; CANN6; Cannabinoid receptor I brain; CB 1; CB R; CB1; CB1A; CB1K5; CbR; Central cannabinoid receptor; Central cannabinoid receptor isoform a; Central cannabinoid recept
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CNR-1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
细胞定位：细胞膜
钙粘蛋白相关的神经受体1抗体产品介绍：background: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009] Function: Involved in cannabinoid-induced CNS effects. Acts by钙粘蛋白相关的神经受体1抗体 inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. Subunit: Interacts (via C-terminus) with CNRIP1. Subcellular Location: Cell membrane. 钙粘蛋白相关的神经受体1抗体Tissue Specificity: Widely expressed. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 1268 Database links: Entrez Gene: 1268 Human Entrez Gene: 12801 Mouse Entrez Gene: 25248 Rat Entrez Gene: 281087 Cow Entrez Gene: 481913 Dog Omim: 114610 Human SwissProt: Q5IS73 Chimpanzee SwissProt: P21554 Human SwissProt: P47746 Mouse SwissProt: P20272 Rat Unigene: 709067 Human Unigene: 75110 Human Unigene: 7992 Mouse Unigene: 222240 Rat Unigene: 89774 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CB1又称**素受体1,可导致**素类物质作用及代谢异常,从而影响胃肠动力及感觉.
钙粘蛋白相关的神经受体1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid