细胞角蛋白72抗体
规格：1mg/1ml
英文名： KRT72
别名： CK-72; Cytokeratin-72; K2C72_HUMAN; K6irs; K6IRS2; K72; KB35; Keratin 6 inner root sheath 2; keratin protein K6irs; Keratin type II cytoskeletal 72; Keratin-72; KRT6; KRT6IRS2; Krt72; Type II inner ro
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KRT72
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：
细胞角蛋白72抗体产品介绍：background: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different 细胞角蛋白72抗体isoforms have been found for this gene.[provided by RefSeq, Jun 2009] Function: Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. Subunit: Heterotetramer of two type I and two type II keratins. Tissue Specificity: Highly expressed in hair follicles from scalp and eyebrow. Also expressed in palmoplantar epidermis. Not expressed in face skin despite the presence of fine hairs histologically. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in细胞角蛋白72抗体Henle or Huxley layers of the IRS. In the IRS cuticle, its presence is delayed up to the height of the apex of the dermal papilla (at protein level). Similarity: Belongs to the intermediate filament family. Gene ID: 140807 Database links: Entrez Gene: 140807 Human Omim: 608246 Human SwissProt: Q14CN4 Human Unigene: 662013 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞角蛋白72抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid