细胞角蛋白23抗体
规格：1mg/1ml
英文名： KRT23
别名： CK 23; CK-23; CK23; Cytokeratin 23; Cytokeratin-23; Cytokeratin23; DKFZP434G032; HAIK 1; HAIK1; Histone deacetylase inducible keratin 23; Hyperacetylation inducible type I keratin; K1C23_HUMAN; K23; K
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KRT23
交叉反应：Human,
细胞定位：
细胞角蛋白23抗体产品介绍：background: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Function: 细胞角蛋白23抗体Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane (By similarity). Subunit: Interacts with ERLEC1 (By similarity). Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Similarity: Contains 1 CUB domain. 细胞角蛋白23抗体Contains 1 kringle domain. Contains 1 WSC domain. Gene ID: 25984 Database links: Entrez Gene: 25984 Human Omim: 606194 Human SwissProt: Q9C075 Human Unigene: 9029 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞角蛋白23抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid